Global mortality from dementia : Application of a new method and results from the Global Burden of Disease Study 2019

Show simple item record GBD 2019 Collaborators Nichols, Emma Abd-Allah, Foad Abdoli, Amir Kivimäki, Mika Meretoja, Atte Shiri, Rahman 2022-02-17T14:55:03Z 2022-02-17T14:55:03Z 2021
dc.identifier.citation GBD 2019 Collaborators , Nichols , E , Abd-Allah , F , Abdoli , A , Kivimäki , M , Meretoja , A & Shiri , R 2021 , ' Global mortality from dementia : Application of a new method and results from the Global Burden of Disease Study 2019 ' , Alzheimer's & Dementia: Translational Research & Clinical Interventions , vol. 7 , no. 1 , 12200 .
dc.identifier.other PURE: 174234298
dc.identifier.other PURE UUID: 26169d37-df05-4b57-bf6a-099b2ae82400
dc.identifier.other WOS: 000750546300025
dc.description.abstract Introduction Dementia is currently one of the leading causes of mortality globally, and mortality due to dementia will likely increase in the future along with corresponding increases in population growth and population aging. However, large inconsistencies in coding practices in vital registration systems over time and between countries complicate the estimation of global dementia mortality. Methods We meta-analyzed the excess risk of death in those with dementia and multiplied these estimates by the proportion of dementia deaths occurring in those with severe, end-stage disease to calculate the total number of deaths that could be attributed to dementia. Results We estimated that there were 1.62 million (95% uncertainty interval [UI]: 0.41-4.21) deaths globally due to dementia in 2019. More dementia deaths occurred in women (1.06 million [0.27-2.71]) than men (0.56 million [0.14-1.51]), largely but not entirely due to the higher life expectancy in women (age-standardized female-to-male ratio 1.19 [1.10-1.26]). Due to population aging, there was a large increase in all-age mortality rates from dementia between 1990 and 2019 (100.1% [89.1-117.5]). In 2019, deaths due to dementia ranked seventh globally in all ages and fourth among individuals 70 and older compared to deaths from other diseases estimated in the Global Burden of Disease (GBD) study. Discussion Mortality due to dementia represents a substantial global burden, and is expected to continue to grow into the future as an older, aging population expands globally. en
dc.format.extent 28
dc.language.iso eng
dc.relation.ispartof Alzheimer's & Dementia: Translational Research & Clinical Interventions
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject burden of disease
dc.subject dementia
dc.subject global health
dc.subject mortality
dc.subject ALL-CAUSE
dc.subject POPULATION
dc.subject SURVIVAL
dc.subject PREDICTORS
dc.subject 3112 Neurosciences
dc.subject 3124 Neurology and psychiatry
dc.title Global mortality from dementia : Application of a new method and results from the Global Burden of Disease Study 2019 en
dc.type Article
dc.contributor.organization Department of Public Health
dc.contributor.organization Clinicum
dc.contributor.organization HUS Neurocenter
dc.contributor.organization Neurologian yksikkö
dc.description.reviewstatus Peer reviewed
dc.relation.issn 2352-8737
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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