Infectious diseases specialist consultation in Staphylococcus lugdunensis bacteremia

Show full item record



Forsblom , E , Högnäs , E , Syrjänen , J & Järvinen , A 2021 , ' Infectious diseases specialist consultation in Staphylococcus lugdunensis bacteremia ' , PLoS One , vol. 16 , no. 10 , e0258511 .

Title: Infectious diseases specialist consultation in Staphylococcus lugdunensis bacteremia
Author: Forsblom, Erik; Högnäs, Emma; Syrjänen, Jaana; Järvinen, Asko
Contributor organization: HUS Inflammation Center
Infektiosairauksien yksikkö
Department of Medicine
Date: 2021-10
Language: eng
Number of pages: 13
Belongs to series: PLoS One
ISSN: 1932-6203
Abstract: Background Commensal coagulase negative Staphylococcus lugdunensis may cause severe bacteremia (SLB) and complications. Treatment of SLB is not fully established and we wanted to evaluate if infectious diseases specialist consultation (IDSC) would improve management and prognosis. Methods Multicenter retrospective study of SLB patients followed for 1 year. Patients were stratified according to bedside (formal), telephone (informal) or lack of IDSC within 7 days of SLB diagnosis. Results Altogether, 104 SLB patients were identified: 24% received formal bedside and 52% informal telephone IDSC whereas 24% were managed without any IDSC. No differences in demographics, underlying conditions or severity of illness were observed between the groups. Patients with bedside IDSC, compared to telephone IDSC or lack of IDSC, had transthoracic echocardiography more often performed (odds ratio [OR] 4.00; 95% confidence interval [CI] 1.31–12.2; p = 0.012) and (OR 16.0; 95% CI, 4.00–63.9; P<0.001). Bedside IDSC was associated with more deep infections diagnosed compared to telephone IDSC (OR, 7.44; 95% CI, 2.58–21.4; p<0.001) or lack of IDSC (OR, 9.56; 95% CI, 2.43–37.7; p = 0.001). The overall mortality was 7%, 10% and 17% at 28 days, 90 days and 1 year, respectively. Considering all prognostic parameters, patients with IDSC, compared to lack of IDSC, had lower 90 days and 1 year mortality (OR, 0.11; 95% CI, 0.02–0.51; p = 0.005) and (OR, 0.22; 95% CI, 0.07–0.67; p = 0.007). Conclusion IDSC may improve management and outcome of Staphylococcus lugdunensis bacteremia.
Description: Publisher Copyright: Copyright: © 2021 Forsblom et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Subject: 3111 Biomedicine
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion

Files in this item

Total number of downloads: Loading...

Files Size Format View
journal.pone.0258511_1_.pdf 645.9Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record