The Cow's Milk-Related Symptom Score (CoMiSS((TM))) : A Useful Awareness Tool

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Bajerova , K , Salvatore , S , Dupont , C , Eigenmann , P , Kuitunen , M , Meyer , R , Ribes-Koninckx , C , Shamir , R , Szajewska , H & Vandenplas , Y 2022 , ' The Cow's Milk-Related Symptom Score (CoMiSS((TM))) : A Useful Awareness Tool ' , Nutrients , vol. 14 , no. 10 , 2059 . https://doi.org/10.3390/nu14102059

Title: The Cow's Milk-Related Symptom Score (CoMiSS((TM))) : A Useful Awareness Tool
Author: Bajerova, Katerina; Salvatore, Silvia; Dupont, Christophe; Eigenmann, Philippe; Kuitunen, Mikael; Meyer, Rosan; Ribes-Koninckx, Carmen; Shamir, Raanan; Szajewska, Hania; Vandenplas, Yvan
Contributor organization: HUS Children and Adolescents
Children's Hospital
Clinicum
Date: 2022-05
Language: eng
Number of pages: 22
Belongs to series: Nutrients
ISSN: 2072-6643
DOI: https://doi.org/10.3390/nu14102059
URI: http://hdl.handle.net/10138/345816
Abstract: The Cow's Milk-related Symptom Score (CoMiSS (TM)) was developed as a clinical tool aimed at increasing the awareness of health care professionals for the presence and intensity of clinical manifestations possibly related to cow's milk (CM) intake. This review summarizes current evidence on CoMiSS. We found twenty-five original studies, one pooled analysis of three studies, and two reviews on CoMiSS. Infants exhibiting symptoms possibly related to CM, present with a higher median CoMiSS (6 to 13; 16 studies) than apparently healthy infants (median from 3 to 4; and mean 3.6-4.7; 5 studies). In children with cow's milk allergy (CMA), 11 studies found that a CoMiSS of >= 12 predicted a favorable response to a CM-free diet; however, sensitivity (20% to 77%) and specificity (54% to 92%) varied. The decrease of CoMiSS during a CM elimination diet was also predictive of a reaction to an oral food challenge to diagnose CMA. A low CoMiSS (
Subject: CoMiSS
cow's milk allergy
food allergy
infant
cow's milk
PROTEIN ALLERGY
HYDROLYZED FORMULA
FOOD ALLERGY
INFANTS
SAFETY
COMISS(TM)
CHILDREN
TRIAL
INDEX
3143 Nutrition
3123 Gynaecology and paediatrics
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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