Can Bacteriophages Replace Antibiotics?

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http://hdl.handle.net/10138/345843

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Skurnik , M 2022 , ' Can Bacteriophages Replace Antibiotics? ' , Antibiotics , vol. 11 , no. 5 , 575 . https://doi.org/10.3390/antibiotics11050575

Title: Can Bacteriophages Replace Antibiotics?
Author: Skurnik, Mikael
Contributor organization: HUMI - Human Microbiome Research
Helsinki One Health (HOH)
Research Programs Unit
Mikael Skurnik / Principal Investigator
HUSLAB
Department of Bacteriology and Immunology
University of Helsinki
Helsinki University Hospital Area
Date: 2022-05
Language: eng
Number of pages: 10
Belongs to series: Antibiotics
ISSN: 2079-6382
DOI: https://doi.org/10.3390/antibiotics11050575
URI: http://hdl.handle.net/10138/345843
Abstract: Increasing antibiotic resistance numbers force both scientists and politicians to tackle the problem, and preferably without any delay. The application of bacteriophages as precision therapy to treat bacterial infections, phage therapy, has received increasing attention during the last two decades. While it looks like phage therapy is here to stay, there is still a lot to do. Medicine regulatory authorities are working to deliver clear instructions to carry out phage therapy. Physicians need to get more practical experience on treatments with phages. In this opinion article I try to place phage therapy in the context of the health care system and state that the use phages for precision treatments will require a seamless chain of events from the patient to the phage therapy laboratory to allow for the immediate application of phages therapeutically. It is not likely that phages will replace antibiotics, however, they will be valuable in the treatment of infections caused by multidrug resistant bacteria. Antibiotics will nevertheless remain the main treatment for a majority of infections.
Subject: antibiotic resistance
bacteriophage
phage therapy
PHAGE THERAPY
IMMUNE-SYSTEM
BACTERIA
3111 Biomedicine
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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