Measuring functional outcome in upper extremity soft-tissue sarcoma : Validation of the Toronto extremity salvage score and the QuickDASH patient-reported outcome instruments

Show full item record



Permalink

http://hdl.handle.net/10138/346381

Citation

Ketola , H , Kask , G , Barner-Rasmussen , I , Tukiainen , E , Blomqvist , C , Laitinen , M K , Kautiainen , H , Kiiski , J & Repo , J P 2022 , ' Measuring functional outcome in upper extremity soft-tissue sarcoma : Validation of the Toronto extremity salvage score and the QuickDASH patient-reported outcome instruments ' , Journal of Plastic, Reconstructive & Aesthetic Surgery , vol. 75 , no. 5 , pp. 1543-1550 . https://doi.org/10.1016/j.bjps.2021.11.081

Title: Measuring functional outcome in upper extremity soft-tissue sarcoma : Validation of the Toronto extremity salvage score and the QuickDASH patient-reported outcome instruments
Author: Ketola, Helena; Kask, Gilber; Barner-Rasmussen, Ian; Tukiainen, Erkki; Blomqvist, Carl; Laitinen, Minna K.; Kautiainen, Hannu; Kiiski, Juha; Repo, Jussi P.
Contributor organization: Plastiikkakirurgian yksikkö
HUS Musculoskeletal and Plastic Surgery
Clinicum
University of Helsinki
Department of Surgery
Department of Oncology
HUS Comprehensive Cancer Center
I kirurgian klinikka (Töölö)
Department of General Practice and Primary Health Care
Helsinki University Hospital Area
Date: 2022-05
Language: eng
Number of pages: 8
Belongs to series: Journal of Plastic, Reconstructive & Aesthetic Surgery
ISSN: 1748-6815
DOI: https://doi.org/10.1016/j.bjps.2021.11.081
URI: http://hdl.handle.net/10138/346381
Abstract: Interest in functional outcome (FO) and health-related quality of life (HRQL) in extremity soft-tissue sarcoma (STS) patients has increased. The aim of this study was to validate two FO questionnaires for upper extremity STS patients: the Toronto Extremity Salvage Score (TESS) and short version of the Disability of Arm, Shoulder and Hand (QuickDASH), based on Finnish population data. A multi-center study was conducted at two academic sarcoma centers. Surgically treated upper extremity STS patients were invited to participate. Patients completed the TESS and the QuickDASH with HRQL questionnaires the 15D and the QLQ-C30. The scores were analyzed and compared. Fifty-five patients with a mean follow-up period of 4.7 years were included. Mean age was 63 years (standard deviation [SD] 14.6). The mean score for TESS was 88.5 (SD 15.1) and for QuickDASH 17.8 (SD 19.6). The QuickDASH had a statistically significantly better score coverage. A ceiling effect was noted, 27% and 20% for TESS and QuickDASH, respectively. The TESS and QuickDASH scores were strongly correlated ( r =-0.89). The TESS score strongly correlated with the QLQ-C30 ( r = 0.79) and the 15D score ( r = 0.70). The QuickDASH score correlated strongly with the QLQ-C30 score ( r =-0.71) and moderately with the 15D score ( r =-0.56). The TESS score had a statistically significantly stronger correlation with the 15D score than QuickDASH ( p < 0.005). Both the TESS and the QuickDASH provide reliable scores for assessing FO in upper extremity STS patients. The QuickDASH has a better coverage, whereas TESS showed a stronger correlation to HRQL scores. (c) 2022 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ )
Subject: Sarcoma
Soft-tissue sarcoma
Outcome measures
Validation
Patient reported outcome measures
QUALITY-OF-LIFE
SCANDINAVIAN SARCOMA
CLINICAL-TRIALS
DISABILITIES
STATISTICS
AMPUTATION
SHOULDER
SURGERY
VERSION
BONE
3126 Surgery, anesthesiology, intensive care, radiology
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


Files in this item

Total number of downloads: Loading...

Files Size Format View
PIIS1748681521006252.pdf 689.9Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record