The prevalence of non-invasive ventilation and long-term oxygen treatment in Helsinki University Hospital area, Finland

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http://hdl.handle.net/10138/346389

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Kotanen , P , Brander , P & Kreivi , H-R 2022 , ' The prevalence of non-invasive ventilation and long-term oxygen treatment in Helsinki University Hospital area, Finland ' , BMC Pulmonary Medicine , vol. 22 , no. 1 , 248 . https://doi.org/10.1186/s12890-022-02044-5

Title: The prevalence of non-invasive ventilation and long-term oxygen treatment in Helsinki University Hospital area, Finland
Author: Kotanen, Petra; Brander, Pirkko; Kreivi, Hanna-Riikka
Contributor organization: HUS Heart and Lung Center
University of Helsinki
Date: 2022-06-25
Language: eng
Number of pages: 10
Belongs to series: BMC Pulmonary Medicine
ISSN: 1471-2466
DOI: https://doi.org/10.1186/s12890-022-02044-5
URI: http://hdl.handle.net/10138/346389
Abstract: Background: Chronic respiratory failure (CRF) can be treated at home with non-invasive ventilation (NIV) and/or long-term oxygen (LTOT). The prevalence of these treatments is largely unknown. We aimed to clarify the prevalence and indications of the treatments, and the three-year mortality of the treated patients in the Helsinki University Hospital (HUH) area in Finland. Methods: In this retrospective study we analyzed the prevalence of adult CRF patients treated with NIV and/or LTOT on 1.1.2018 and followed these patients until 1.1.2021. Data collected included the underlying diagnosis, patient characteristics, information on treatment initiation and from the last follow-up visit, and mortality during the three-year follow-up. Patients with home invasive mechanical ventilation or sleep apnea were excluded. Results: On 1.1.2018, we had a total of 815 patients treated with NIV and/or LTOT in the Helsinki University Hospital (HUH) area, with a population of 1.4 million. The prevalence of NIV was 35.4 per 100,000, of LTOT 24.6 per 100,000 and of the treatments combined 60.0 per 100,000. Almost half, 44.5%, were treated with NIV, 41.0% with LTOT, and 14.4% underwent both. The most common diagnostic groups were chronic obstructive pulmonary disease (COPD) (33.3%) and obesity-hypoventilation syndrome (OHS) (26.6%). The three-year mortality in all patients was 45.2%. In the COPD and OHS groups the mortality was 61.3% and 21.2%. In NIV treated patients, the treatment durations varied from COPD patients 5.3 years to restrictive chest wall disease patients 11.4 years. The age-adjusted Charlson co-morbidity index (ACCI) median for all patients was 3.0. Conclusions: NIV and LTOT are common treatments in CRF. The prevalence in HUH area was comparable to other western countries. As the ACCI index shows, the treated patients were fragile, with multiple co-morbidities, and their mortality was high. Treatment duration and survival vary greatly depending on the underlying diagnosis.
Subject: Non-invasive ventilation
Long-term oxygen treatment
Prevalence
Mortality
Chronic respiratory failure
COPD
POSITIVE-PRESSURE VENTILATION
CHRONIC RESPIRATORY-FAILURE
THERAPY
DISEASE
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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