Effects of post partum administration of ketoprofen on sow health and piglet growth

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Viitasaari , E , Hänninen , L , Heinonen , M , Raekallio , M , Orro , T , Peltoniemi , O & Valros , A 2013 , ' Effects of post partum administration of ketoprofen on sow health and piglet growth ' , The Veterinary Journal , vol. 198 , no. 1 , pp. 153-157 . https://doi.org/10.1016/j.tvjl.2013.06.013

Title: Effects of post partum administration of ketoprofen on sow health and piglet growth
Alternative title: Porsimisen jälkeen annetun ketoprofeenin vaikutukset emakon terveyteen ja porsaiden kasvuun
Author: Viitasaari, Elina; Hänninen, Laura; Heinonen, Mari; Raekallio, Marja; Orro, Toomas; Peltoniemi, Olli; Valros, Anna
Other contributor: University of Helsinki, Departments of Faculty of Veterinary Medicine
University of Helsinki, Departments of Faculty of Veterinary Medicine
University of Helsinki, Departments of Faculty of Veterinary Medicine
University of Helsinki, Departments of Faculty of Veterinary Medicine
University of Helsinki, Departments of Faculty of Veterinary Medicine
University of Helsinki, Departments of Faculty of Veterinary Medicine





Date: 2013
Language: eng
Number of pages: 5
Belongs to series: The Veterinary Journal
ISSN: 1090-0233
DOI: https://doi.org/10.1016/j.tvjl.2013.06.013
URI: http://hdl.handle.net/10138/42727
Abstract: The effect of the non-steroidal anti-inflammatory drug ketoprofen on the post-farrowing phase of sows was studied in a randomized, blinded, placebo-controlled trial. Ketoprofen (3 mg/kg) was administered intramuscularly to 20 healthy sows for 3 days post partum (p.p.). The control group (n=20) received a saline placebo. Backfat, number of days of constipation and days before feed refusal were measured. Body condition (BCS) and shoulder sores were scored during a week p.p. Changes in BCS, backfat and shoulder sore scores were analysed with ANOVA. Blood was collected on days -1, 0, 5 and 14 with respect to medication. Aspartate aminotransferase (AST), creatinine kinase (CK), haptoglobin and serum amyloid A (SAA) were quantified and analysed with a Mann-Whitney U test. BCS and backfat decreased less following ketoprofen administration than with the placebo (-0.08 ± 0.2 vs. -0.8 ± 0.2, 1.0 ± 0.8 mm vs. -2.0 ± 0.9 mm, respectively, P<0.05 for both) during the first 2 weeks of lactation. The shoulder sore score deterioration was milder during days 4-6 p.p with ketoprofen than with the placebo (P<0.05). Duration of constipation was shorter with ketoprofen than with the placebo (5.5 ± 0.3 vs. 6.4 ± 0.3 days p.p. P<0.05). Incidences of feed refusal occurred later in the ketoprofen than in the placebo group (9.6 ± 0.9 vs. 3.8 ± 0.8 days p.p., P<0.05). AST and SAA were higher after ketoprofen than placebo on day 5 p.p. (P<0.05). Ketoprofen benefits sows during the first 2 weeks post farrowing, but apparently causes some tissue irritation.
Subject: 413 Veterinary science
sow
farrowing
ketoprofen
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