Effects of post partum administration of ketoprofen on sow health and piglet growth

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dc.contributor.author Viitasaari, Elina
dc.contributor.author Hänninen, Laura
dc.contributor.author Heinonen, Mari
dc.contributor.author Raekallio, Marja
dc.contributor.author Orro, Toomas
dc.contributor.author Peltoniemi, Olli
dc.contributor.author Valros, Anna
dc.date.accessioned 2014-02-05T22:15:20Z
dc.date.available 2014-02-05T22:15:20Z
dc.date.issued 2013
dc.identifier.citation Viitasaari , E , Hänninen , L , Heinonen , M , Raekallio , M , Orro , T , Peltoniemi , O & Valros , A 2013 , ' Effects of post partum administration of ketoprofen on sow health and piglet growth ' , The Veterinary Journal , vol. 198 , no. 1 , pp. 153-157 . https://doi.org/10.1016/j.tvjl.2013.06.013
dc.identifier.other PURE: 26525809
dc.identifier.other PURE UUID: c44e12ea-80e9-41c1-8551-401bf99bdd0e
dc.identifier.other WOS: 000328305300029
dc.identifier.other Scopus: 84887613399
dc.identifier.other ORCID: /0000-0002-9481-1837/work/29849841
dc.identifier.other ORCID: /0000-0002-5732-0692/work/28880680
dc.identifier.other ORCID: /0000-0001-5118-8451/work/28761912
dc.identifier.other ORCID: /0000-0002-4431-3346/work/48607319
dc.identifier.uri http://hdl.handle.net/10138/42727
dc.description.abstract The effect of the non-steroidal anti-inflammatory drug ketoprofen on the post-farrowing phase of sows was studied in a randomized, blinded, placebo-controlled trial. Ketoprofen (3 mg/kg) was administered intramuscularly to 20 healthy sows for 3 days post partum (p.p.). The control group (n=20) received a saline placebo. Backfat, number of days of constipation and days before feed refusal were measured. Body condition (BCS) and shoulder sores were scored during a week p.p. Changes in BCS, backfat and shoulder sore scores were analysed with ANOVA. Blood was collected on days -1, 0, 5 and 14 with respect to medication. Aspartate aminotransferase (AST), creatinine kinase (CK), haptoglobin and serum amyloid A (SAA) were quantified and analysed with a Mann-Whitney U test. BCS and backfat decreased less following ketoprofen administration than with the placebo (-0.08 ± 0.2 vs. -0.8 ± 0.2, 1.0 ± 0.8 mm vs. -2.0 ± 0.9 mm, respectively, P<0.05 for both) during the first 2 weeks of lactation. The shoulder sore score deterioration was milder during days 4-6 p.p with ketoprofen than with the placebo (P<0.05). Duration of constipation was shorter with ketoprofen than with the placebo (5.5 ± 0.3 vs. 6.4 ± 0.3 days p.p. P<0.05). Incidences of feed refusal occurred later in the ketoprofen than in the placebo group (9.6 ± 0.9 vs. 3.8 ± 0.8 days p.p., P<0.05). AST and SAA were higher after ketoprofen than placebo on day 5 p.p. (P<0.05). Ketoprofen benefits sows during the first 2 weeks post farrowing, but apparently causes some tissue irritation. en
dc.format.extent 5
dc.language.iso eng
dc.relation.ispartof The Veterinary Journal
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject 413 Veterinary science
dc.subject sow
dc.subject farrowing
dc.subject ketoprofen
dc.title Effects of post partum administration of ketoprofen on sow health and piglet growth en
dc.title.alternative Porsimisen jälkeen annetun ketoprofeenin vaikutukset emakon terveyteen ja porsaiden kasvuun fi
dc.type Article
dc.contributor.organization Departments of Faculty of Veterinary Medicine
dc.contributor.organization Production Animal Medicine
dc.contributor.organization Equine and Small Animal Medicine
dc.contributor.organization Research Centre for Animal Welfare
dc.contributor.organization Animal Reproduction Science
dc.contributor.organization Teachers' Academy
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.tvjl.2013.06.013
dc.relation.issn 1090-0233
dc.rights.accesslevel openAccess
dc.type.version publishedVersion
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S1090023313002979

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