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  • Lehtonen, J.T.; Mustonen, O.; Ramiarinjanahary, H.; Niemelä, J.; Rita, H. (Kluwer Academic Publishers, 2001)
    We used logistic and Poisson regression models to determine factors of forest and landscape structure that influence the presence and abundance of rodent species in the rain forest of Ranomafana National Park in southeastern Madagascar. Rodents were collected using live-traps along a gradient of human disturbance. All five endemic rodent species (Nesomys rufus, N. audeberti, Eliurus tanala, E. minor and E. webbi) and the introduced rat Rattus rattus were captured in both secondary and primary forests, but the introduced Mus musculus was only trapped in secondary forest. The abundance of R. rattus increased with the level of habitat disturbance, and it was most common in the heavily logged secondary forest. Furthermore, the probability of the presence of R. rattus increased with decreasing distance from forest edge and decreasing canopy cover, while the probability of presence increased with increasing herbaceous cover, altitude and overstory tree height. The species was never observed farther than 500 m away from human habitation or camp-site. N. rufus prefered selectively-logged forest at altitudes above 900 m a.s.l. Its probability of presence increased with increasing canopy cover, herbaceous cover and distance from forest edge, and with decreasing density of fallen logs, overstory tree height and distance from human habitation. N. audeberti prefered heavily-logged areas, while E. tanala was the only species occurring along the entire range of forest disturbance. We suggest that in the Ranomafana National Park the spread of R. rattus is associated with deforestation.
  • Ridell, J.; Siitonen, A.; Paulin, L.; Mattila, L.; Korkeala, H.; Albert, M.J. (American Society for Microbiology, 1994)
    We found an epidemiological association of Hafnia alvei with diarrhea, because the organism was isolated from 12 of 77 (16%) adult Finnish tourists to Morocco who developed diarrhea and from 0 of 321 tourists without diarrhea (P < 0.001). From another group of 112 adult Finnish diarrheal patients, only 2 (2%) yielded H. alvei. In contrast to some Bangladeshi strains of H. alvei, the Finnish strains were negative for the attachment-effacement lesion by an in vitro fluorescent acting staining test and also did not show homology to the Escherichia coli attachment-effacement gene (eaeA) by PCR. These results suggest that a mechanism or mechanisms other than the attachment-effacement lesion may also be involved in the association of H. alvei with diarrhea.
  • Lodenius, M.; Seppänen, A. (Pergamon Press Ltd., 1982)
  • Vihavainen, Timo (Venäjän ja Itä-Euroopan tutkimuksen seura, 1994)
  • Nurminen, Janne; Puustinen, Juha; Lähteenmäki, Ritva; Vahlberg, Tero; Lyles, Alan; Partinen, Markku; Räihä, Ismo; Neuvonen, Pertti J; Kivelä, Sirkka-Liisa (BioMed Central Ltd, 2014)
    Abstract Background Benzodiazepines and related drugs affect physical functioning negatively and increase fall and fracture risk. As impaired muscle strength and balance are risk factors for falls, we examined the effects of hypnotic withdrawal on handgrip strength and balance in older adult outpatients during and after long-term use of temazepam, zopiclone and zolpidem (here collectively referred to as &#8220;benzodiazepines&#8221;). Methods Eighty-nine chronic users (59 women, 30 men) of temazepam, zopiclone or zolpidem aged &#8805;55&#160;years participated in a benzodiazepine withdrawal study. Individual physician-directed withdrawal was performed gradually over a one-month period and participants were followed up to six months. Handgrip strength was assessed using a handheld dynamometer, and balance using the Short Berg&#8217;s Balance Scale during the period of benzodiazepine use (baseline), and at 1, 2, 3 weeks, and 1, 2 and 6 months after initiating withdrawal. Withdrawal outcome and persistence were determined by plasma benzodiazepine-determinations at baseline and at four weeks (&#8220;short-term withdrawers&#8221;, n = 69; &#8220;short-term non-withdrawers&#8221;, n = 20), and by interviews at six months (&#8220;long-term withdrawers&#8221;, n = 34; &#8220;long-term non-withdrawers&#8221;, n = 55). Also most of the non-withdrawers markedly reduced their benzodiazepine use. Results Within three weeks after initiating withdrawal, handgrip strength improved significantly (P&#8201;&#8804;&#8201;0.005) compared to baseline values. Among women, long-term withdrawers improved their handgrip strength both when compared to their baseline values (P = 0.001) or to non-withdrawers (P =0.004). In men, improvement of handgrip strength from baseline was not significantly better in withdrawers than in non-withdrawers. However, men did improve their handgrip strength values compared to baseline (P = 0.002). Compared to balance test results at baseline, withdrawers improved starting from the first week after withdrawal initiation. There was, however, only a borderline difference (P = 0.054) in balance improvement between the long-term withdrawers and long-term non-withdrawers. Of note, the non-withdrawers tended to improve their handgrip strength and balance compared to baseline values, in parallel with their reduced benzodiazepine use. Conclusions Withdrawal from long-term use of benzodiazepines can rapidly improve muscle strength and balance. Our results encourage discontinuing benzodiazepine hypnotics, particularly in older women who are at a high risk of falling and sustaining fractures. Trial registration EU Clinical Trials Register: EudraCT2008000679530. Registered 31 October 2008
  • Kaartinen, Timo (University of Illinois Press, 2013)
    The topic of this article is the reproduction of tradition among the Bandanese, an Eastern Indonesian people. I analyze the style and rhetoric of songs that tell about ancestral sea voyages. The question I address is what happens to the value of the songs as tradition when they turn from oral performances into circulating texts. I explore several contexts of performance and transmission and argue that the songs can be embedded in lived realities in different ways. By writing the songs down, the Bandanese reorganize their tradition into new genres of text and performance. Their metadiscourse of tradition affirms that these genres represent the exemplary, complete language of the ancestors. Although singers and writers affirm the artistic, textual, and cultural completeness of their arts, they are reluctant to pass on their knowledge in an already integrated form.
  • Strandin Tomas; Hepojoki Jussi; Wang Hao; Vaheri Antti; Lankinen Hilkka (2008)
    BACKGROUND: We have previously reported that the apathogenic Tula hantavirus induces apoptosis in Vero E6 epithelial cells. To assess the molecular mechanisms behind the induced apoptosis we studied the effects of hantavirus infection on cellular signaling pathways which promote cell survival. We previously also observed that the Tula virus-induced cell death process is augmented by external TNF-a ... [More]
  • HaploRec 
    Eronen, Lauri; Geerts, Floris; Toivonen, Hannu (BIOMED CENTRAL LTD, 2006)
  • Mälksoo, Maria (University of Cambridge (Memory at War-research group), 2012)
  • Roinila, Markku (Eurooppalaisen filosofian seura, 2009)
  • Toivanen, Jukka; Järvisalo, Matti; Toivonen, Hannu (2013)
  • Sanz-Garcia, Andres; Oliver-De-La-Cruz, Jorge; Mirabet, Vicente; Gandia, Carolina; Villagrasa, Alejandro; Sodupe, Enrique; Escobedo-Lucea, Carmen (Cambridge University Press, 2015)
    Heart disease, including valve pathologies, is the leading cause of death worldwide. Despite the progress made thanks to improving transplantation techniques, a perfect valve substitute has not yet been developed: once a diseased valve is replaced with current technologies, the newly implanted valve still needs to be changed some time in the future. This situation is particularly dramatic in the case of children and young adults, because of the necessity of valve growth during the patient's life. Our review focuses on the current status of heart valve (HV) therapy and the challenges that must be solved in the development of new approaches based on tissue engineering. Scientists and physicians have proposed tissue-engineered heart valves (TEHVs) as the most promising solution for HV replacement, especially given that they can help to avoid thrombosis, structural deterioration and xenoinfections. Lastly, TEHVs might also serve as a model for studying human valve development and pathologies.
  • Voigt, H.-R. (Estonian Marine Institute, 2004)
  • Heliövaara, K.; Väisänen, R.; Kemppi, E.; Lodenius, M. (Entomologica Fennica ry., 1990)
  • Heliövaara, K.; Väisänen, R.; Braunschweiler, H.; Lodenius, M. (Elsevier, 1987)
  • Lodenius, M.; Ak'Habuhaya, J.; Rusibamayila, C. (Karolinum-Nakladatelstvi Univerzity Karlovy, 1996)