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Somatic mutation analysis of MYH11 in breast and prostate cancer.

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dc.contributor Haartman-instituutti (Kliinisteoreettinen laitos) en
dc.contributor Lääketieteellisen genetiikan osasto (Kliinisteoreettinen laitos. Haartman-instituutti) en
dc.contributor.author Alhopuro Pia en
dc.contributor.author Karhu Auli en
dc.contributor.author Winqvist Robert en
dc.contributor.author Waltering Kati en
dc.contributor.author Visakorpi Tapio en
dc.contributor.author Aaltonen Lauri A en
dc.date 2008 en
dc.date.accessioned 2008-11-14T10:27:22Z en
dc.date.accessioned 2009-06-24T10:25:38Z
dc.date.available 2008-11-14T10:27:22Z en
dc.date.available 2009-06-24T10:25:38Z
dc.date.issued 2008-11-14T10:27:22Z en
dc.identifier.issn 1471-2407 en
dc.identifier.uri 10.1186/1471-2407-8-263 en
dc.identifier.uri http://hdl.handle.net/10250/3188
dc.description.abstract BACKGROUND: MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia. We have previously shown that MYH11 mutations occur in human colorectal cancer, and may also be associated with Peutz-Jeghers syndrome. The mutations ... [More] en
dc.language.iso eng en
dc.relation.ispartof BMC Cancer en
dc.rights green en
dc.subject Adenocarcinoma en
dc.subject Adult en
dc.subject Aged en
dc.subject Aged, 80 and over en
dc.subject Breast Neoplasms en
dc.subject Cell Line, Tumor en
dc.subject Exons en
dc.subject Female en
dc.subject Humans en
dc.subject Male en
dc.subject Middle Aged en
dc.subject Mutation, Missense en
dc.subject Myosin Heavy Chains en
dc.subject Prostatic Neoplasms en
dc.title Somatic mutation analysis of MYH11 in breast and prostate cancer. en
dc.type Journal Article en
dc.identifier.laitoskoodi 3603 en
dc.creator.corporateName Lääketieteellisen genetiikan osasto (Kliinisteoreettinen laitos. Haartman-instituutti) fi
dc.creator.corporateName Department of Medical Genetics (Haartman Institute) en
dc.creator.corporateName Medicinsk genetik, Avdelningen för (Kliniskteoretiska institutionen. Haartman-institutet) sv
dc.identifier.pubmedid 18796164 en
dc.format.volume 8 en
dc.format.startpage 263 en
dc.identifier.nlmid 100967800 en

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