Lindgren, MaijaNumminen, LindaHolm, MinnaTherman, SebastianTuulio-Henriksson, Annamari2022-09-222022-09-222022-06Lindgren, M, Numminen, L, Holm, M, Therman, S & Tuulio-Henriksson, A 2022, 'Psychotic-like experiences of young adults in the general population predict mental disorders', Psychiatry Research, vol. 312, 114543. https://doi.org/10.1016/j.psychres.2022.114543ORCID: /0000-0002-3580-3693/work/119578255http://hdl.handle.net/10138/348274Psychotic-like experiences (PLEs) have been identified as risk markers for psychotic disorders and may indicate an individual's susceptibility to mental disorders in general. We examined whether 23 PLEs (assessed with MCIDI questionnaire) reported in young adulthood (n = 1313) predict subsequent psychotic or any mental disorders in the general population. We also investigated whether these possible associations are explained by general psychological distress assessed with the General Health Questionnaire-12 (GHQ-12). The register follow-up period spanned 10-12 years. In Cox regression models, PLEs predicted subsequent psychotic disorders (n = 12) when the effects of age, sex, education, and marital status were adjusted for, but not when general psychological distress was added to the model. Having any mental disorders during follow-up (n = 91) was predicted by PLEs reported at a younger age, when controlling for age, sex, education, marital status, and general psychological distress. In line with earlier results in other age groups, PLEs can be seen as a sign of vulnerability to not just psychotic but all mental disorders during the following years also among young adults in the general population. PLEs were a predictive marker of general psychopathology independently from general psychological distress.7engcc_byinfo:eu-repo/semantics/openAccessCIDIGeneral populationGeneral psychological distressPsychiatric disorderPsychosisRegister follow-upHIGH-RISKCOMMUNITY SAMPLESYMPTOMSHEALTHPEOPLESCHIZOPHRENIAASSOCIATIONSMETAANALYSISDEPRESSIONILLNESSPsychologyArticleopenAccessb2883a50-65a4-4d87-9ad6-4b2f1b61a03e000821199300011