TY - T1 - β2-integrin-mediated leukocyte mechanotransduction and immune responses SN - / UR - URN:ISBN:978-951-51-6019-5; http://hdl.handle.net/10138/314186 T3 - A1 - Guenther, Carla A2 - PB - Helsingin yliopisto Y1 - 2020 LA - eng AB - Our health is protected by the immune system, which maintains a carefully regulated balance between inflammation and immune suppression. To mediate homeostasis and inflammation, leukocytes continuously patrol the body and therefore operate in a dynamic mechanical landscape. Mechanical information is transduced into the cell via different proteins, including adhesion receptors called β2-integrins. These receptors mediate essential leukocyte processes, including phagocytosis, immune cell trafficki... VO - IS - SP - OP - KW - immunobiology N1 - PP - ER -