TY  -  
T1  - κ-Opioidireseptoriantagonistien vaikutus rottien alkoholin juomisen retkahtamisalttiuteen 
SN  -  /  
UR  - URN:NBN:fi-fe201801151387; http://hdl.handle.net/10138/230266 
T3  -  
A1  - Eteläinen, Tony 
A2  -  
PB  - Helsingfors universitet 
Y1  - 2017 
LA  - fin 
AB  - lcohol addiction is a significant public health problem worldwide, and its treatment is extremely challenging. One major problem in the treatment of alcohol addiction are the later relapses to uncontrollable drinking. Approximately 60-70 % of addicts relapse to drinking within a year from the beginning of the treatment. The current treatment of alcohol addiction is based on a combined psychotheraphy and pharmacological treatments, but even at the best the efficacy remains quite modest. This is w... 
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KW  - JDTic; alcohol addiction; relapse; endogenous opioid system; κ-opioid receptor; ADE-model; Long-Evans rat; retkahtaminen; endogeeninen opioidijärjestelmä; κ-opioidireseptori; ADE-malli; Long-Evans -rotta; alkoholiriippuvuus; Farmakologi; Pharmacology; Farmakologia 
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ER  -