TY - T1 - A New Paired Associative Stimulation Protocol with High-Frequency Peripheral Component and High-Intensity 20 Hz Repetitive Transcranial Magnetic Stimulation-A Pilot Study SN - / UR - http://hdl.handle.net/10138/337679 T3 - A1 - Sathyan, Sabin; Tolmacheva, Aleksandra; Tugin, Sergei; Mäkelä, Jyrki P.; Shulga, Anastasia; Lioumis, Pantelis A2 - PB - Y1 - 2021 LA - eng AB - Paired associative stimulation (PAS) is a stimulation technique combining transcranial magnetic stimulation (TMS) and peripheral nerve stimulation (PNS) that can induce plastic changes in the human motor system. A PAS protocol consisting of a high-intensity single TMS pulse given at 100% of stimulator output (SO) and high-frequency 100-Hz PNS train, or "the high-PAS " was designed to promote corticomotoneuronal synapses. Such PAS, applied as a long-term intervention, has demonstrated therapeutic... VO - IS - SP - OP - KW - corticospinal tract; long interval cortical inhibition; neuroplasticity; paired associative stimulation; peripheral nerve stimulation; primary motor cortex; spinal cord injury; transcranial magnetic stimulation; HUMAN MOTOR CORTEX; SPINAL-CORD-INJURY; TIMING-DEPENDENT PLASTICITY; LTP-LIKE PLASTICITY; CORTICAL EXCITABILITY; INHIBITION; CONDUCTION; INDUCTION; FACILITATION; MECHANISMS; 3142 Public health care science, environmental and occupational health N1 - PP - ER -