TY - T1 - A comparative characterization of different host-sourced Lactobacillus ruminis strains and their adhesive, inhibitory, and immunomodulating functions SN - / UR - http://hdl.handle.net/10138/182783 T3 - A1 - Yu, Xia; Åvall-Jääskeläinen, Silja; Koort, Joanna; Lindholm, Agneta; Rintahaka, Johanna; von Ossowski, Ingemar; Palva, Airi; Hynönen, Ulla A2 - PB - Y1 - 2017 LA - eng AB - Lactobacillus ruminis, an autochthonous member of the gastrointestinal microbiota of humans and many animals, is a less characterized but interesting species for many reasons, including its intestinal prevalence and possible positive roles in host-microbe crosstalk. In this study, we isolated a novel L. ruminis strain (GRL 1172) from porcine feces and analyzed its functional characteristics and niche adaptation factors in parallel with those of three other L. ruminis strains (a human isolate, AT... VO - IS - SP - OP - KW - 1183 Plant biology, microbiology, virology; Lactobacillus ruminis; adhesion; inhibition of pathogens; barrier function; TLRs; ENTEROTOXIGENIC ESCHERICHIA-COLI; INNATE IMMUNE-RESPONSE; RHAMNOSUS GG; EPITHELIAL BARRIER; CACO-2 CELLS; BACTERIAL FLAGELLIN; PROBIOTIC BACTERIA; GENOME SEQUENCES; INTESTINAL-CELLS; MEMBRANE BARRIER N1 - PP - ER -