TY - T1 - A comprehensive and high-quality collection of Escherichia coli genomes and their genes SN - / UR - http://hdl.handle.net/10138/328629 T3 - A1 - Horesh, Gal; Blackwell, Grace A.; Tonkin-Hill, Gerry; Corander, Jukka; Heinz, Eva; Thomson, Nicholas R. A2 - PB - Y1 - 2021 LA - eng AB - Escherichia coli is a highly diverse organism that includes a range of commensal and pathogenic variants found across a range of niches and worldwide. In addition to causing severe intestinal and extraintestinal disease, E. coli is considered a priority pathogen due to high levels of observed drug resistance. The diversity in the E. coli population is driven by high genome plasticity and a very large gene pool. All these have made E. coli one of the most well- studied organisms, as well as a com... VO - IS - SP - OP - KW - antimicrobial resistance; Escherichia coli; horizontal gene transfer; pan-genome; Shigella; POPULATION-STRUCTURE; IDENTIFICATION; SEQUENCE; PATHOGENICITY; ANNOTATION; BACTERIAL; TOOL; 1184 Genetics, developmental biology, physiology N1 - PP - ER -