TY  -  
T1  - A convenient and efficient synthesis of thiazolidin-4-ones via cyclization of substituted hydrazinecarbothioamides 
SN  -  /  
UR  - http://hdl.handle.net/10138/298897 
T3  -  
A1  - Hassan, Alaa A.; Mohamed, Nasr K.; El-Shaieb, Kamal M. A.; Tawfeek, Hendawy N.; Bräse, Stefan; Nieger, Martin 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - 2-Substituted hydrazinecarbothioamides and N ,2-disubstituted hydrazinecarbothioamides react in high yield with dimethyl acetylenedicarboxylate (DMAD) to give 4-oxo-Z-(thiazolidin-5-ylidene) acetate derivatives. Several mechanistic options involving interaction are presented. The structures of thiazolidin-4-ones have been unambiguously confirmed by single crystal X-ray crystallography. (C) 2014 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.... 
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IS  -  
SP  -  
OP  -  
KW  - Hydrazinecarbothioamides; Dimethyl acetylenedicarboxylate; Thiazolidin-4-ones; X-ray crystallography; BIOLOGICAL EVALUATION; DERIVATIVES; FACILE; THIAZOLES; DESIGN; POTENT; 116 Chemical sciences 
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ER  -