TY - T1 - A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects SN - / UR - http://hdl.handle.net/10138/239256 T3 - A1 - Sloan, Tim J.; Jalanka, Jonna; Major, Giles A. D.; Krishnasamy, Shanthi; Pritchard, Sue; Abdelrazig, Salah; Korpela, Katri; Singh, Gulzar; Mulvenna, Claire; Hoad, Caroline L.; Marciani, Luca; Barrett, David A.; Lomer, Miranda C. E.; de Vos, Willem M.; Gowland, Penny A.; Spiller, Robin C. A2 - PB - Y1 - 2018 LA - eng AB - Background & aims Ingestion of poorly digested, fermentable carbohydrates (fermentable oligo-, di-, mono-saccharides and polyols; FODMAPs) have been implicated in exacerbating intestinal symptoms and the reduction of intake with symptom alleviation. Restricting FODMAP intake is believed to relieve colonic distension by reducing colonic fermentation but this has not been previously directly assessed. We performed a randomised controlled trial comparing the effect of a low FODMAP diet combined wit... VO - IS - SP - OP - KW - IRRITABLE-BOWEL-SYNDROME; RANDOMIZED CONTROLLED-TRIAL; REDUCES SYMPTOMS; GUT MICROBIOTA; BIFIDOBACTERIA; INULIN; TIME; MRI; PREBIOTICS; BACTERIAL; 3111 Biomedicine N1 - PP - ER -