TY  -  
T1  - A minitablet formulation made from electrospun nanofibers 
SN  -  /  
UR  - http://hdl.handle.net/10138/299389 
T3  -  
A1  - Poller, Bettina; Strachan, Clare; Broadbent, Roland; Walker, Greg F. 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - The purpose of this study was to evaluate electrospun drug loaded nanofibers as a new matrix for mini tablets. Prednisone, a poorly water-soluble drug, was loaded into povidone (polyvinylpyrrolidone, PVP) nanofibers using the process of electrospinning. The drug-loaded nanofiber mat was compressed into minitablets with a 2 mm diameter and a height of 2.63 0.04 mm. SEM analysis of the minitablet identified a nano-web structure with a nanofiber diameter in the range of 400-500 nm. The minitablets ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - POLYVINYLPYRROLIDONE FIBER MATS; WATER-SOLUBLE DRUGS; MINI-TABLETS; DOSAGE FORMS; DELIVERY; INDOMETHACIN; DISPERSIONS; CHILDREN; STATE; DISSOLUTION; 317 Pharmacy 
N1  -   
PP  -  
ER  -