TY  -  
T1  - A single dose of mirtazapine attenuates neural responses to self-referential processing 
SN  -  /  
UR  - http://hdl.handle.net/10138/223848 
T3  -  
A1  - Komulainen, Emma; Heikkila, Roope; Meskanen, Katarina; Raij, Tuukka T.; Nummenmaa, Lauri; Lahti, Jari; Jylhä, Pekka; Melartin, Tarja; Harmer, Catherine J.; Isometsa, Erkki; Ekelund, Jesper 
A2  -  
PB  -  
Y1  - 2016 
LA  - eng 
AB  - Increased self-focus is a core factor in the psychopathology of depression. Cortical midline structures (CMS) are implicated in the neurobiology of self, depression and antidepressant treatment response. Mirtazapine, an antidepressant that increases serotonin and norepinephrine release, enhances processing of positive and attenuates processing of negative emotional information in healthy volunteers after a single dose. These early changes, which are opposite to the negative information bias in d... 
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KW  - Antidepressant; mirtazapine; fMRI; emotions; self-referential processing; MAJOR DEPRESSIVE DISORDER; MEDIAL PREFRONTAL CORTEX; FUNCTIONAL MAGNETIC-RESONANCE; DEFAULT-MODE NETWORK; HEALTHY-VOLUNTEERS; NEURONAL RESPONSES; SELECTIVE SEROTONIN; AMYGDALA REACTIVITY; EMOTIONAL FACES; ANXIETY; 515 Psychology; 3124 Neurology and psychiatry 
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ER  -