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T1  - A splice donor variant in CCDC189 is associated with asthenospermia in Nordic Red dairy cattle 
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UR  - http://hdl.handle.net/10138/311065 
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A1  - Iso-Touru, Terhi; Wurmser, Christine; Venhoranta, Heli; Hiltpold, Maya; Savolainen, Tujia; Sironen, Anu; Fischer, Konrad; Flisikowski, Krzysztof; Fries, Ruedi; Vicente-Carrillo, Alejandro; Alvarez-Rodriguez, Manuel; Nagy, Szabolcs; Mutikainen, Mervi; Peippo, Jaana; Taponen, Juhani; Sahana, Goutam; Guldbrandtsen, Bernt; Simonen, Henri; Rodriguez-Martinez, Heriberto; Andersson, Magnus; Pausch, Hubert 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Background: Cattle populations are highly amenable to the genetic mapping of male reproductive traits because longitudinal data on ejaculate quality and dense microarray-derived genotypes are available for thousands of artificial insemination bulls. Two young Nordic Red bulls delivered sperm with low progressive motility (i.e., asthenospermia) during a semen collection period of more than four months. The bulls were related through a common ancestor on both their paternal and maternal ancestry. ... 
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KW  - Male infertility; Sterility; Immotile sperm; Cattle; CCDC189; DYNEIN REGULATORY COMPLEX; IN-VITRO FERTILIZATION; SPERM MOTILITY; MALE-INFERTILITY; NONSENSE MUTATION; PARAMETERS; CILIARY; DEFICIENCY; GENERATION; MORPHOLOGY; 413 Veterinary science 
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