TY - T1 - A subpopulation of arenavirus nucleoprotein localizes to mitochondria SN - / UR - http://hdl.handle.net/10138/337313 T3 - A1 - Baggio, Francesca; Hetzel, Udo; Nufer, Lisbeth; Kipar, Anja; Hepojoki, Jussi A2 - PB - Y1 - 2021 LA - eng AB - Viruses need cells for their replication and, therefore, ways to hijack cellular functions. Mitochondria play fundamental roles within the cell in metabolism, immunity and regulation of homeostasis due to which some viruses aim to alter mitochondrial functions. Herein we show that the nucleoprotein (NP) of arenaviruses enters the mitochondria of infected cells, affecting the mitochondrial morphology. Reptarenaviruses cause boid inclusion body disease (BIBD) that is characterized, especially in b... VO - IS - SP - OP - KW - INCLUSION-BODY DISEASE; PROTEIN IMPORT; VIRUS NUCLEOPROTEIN; INNATE; INHIBITION; SNAKES; IDENTIFICATION; TRANSLOCASE; INDUCTION; RESPONSES; 11832 Microbiology and virology N1 - PP - ER -