TY  -  
T1  - Abnormal brain development of monoamine oxidase mutant zebrafish and impaired social interaction of heterozygous fish 
SN  -  /  
UR  - http://hdl.handle.net/10138/343331 
T3  -  
A1  - Baronio, Diego; Chen, Yu-Chia; Panula, Pertti 
A2  -  
PB  -  
Y1  - 2022 
LA  - eng 
AB  - Monoamine oxidase (MAO) deficiency and imbalanced levels of brain monoamines have been associated with developmental delay, neuropsychiatric disorders and aggressive behavior. Animal models are valuable tools to gain mechanistic insight into outcomes associated with MAO deficiency. Here, we report a novel genetic model to study the effects of mao loss of function in zebrafish. Quantitative PCR, in situ hybridization and immunocytochemistry were used to study neurotransmitter systems and expressi... 
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KW  - Dopamine; Serotonin; Histamine; Monoamine oxidase; Autism; SEROTONIN TRANSPORTER; HISTAMINERGIC SYSTEM; AUTISM SEVERITY; POINT MUTATION; BEHAVIOR; CHILDREN; MICE; AMPHETAMINE; ASSOCIATION; DISORDER; 3111 Biomedicine 
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ER  -