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T1  - Active mmp-8 quantitative test as an adjunctive tool for early diagnosis of periodontitis 
SN  -  /  
UR  - http://hdl.handle.net/10138/335315 
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A1  - Hernández, Marcela; Baeza, Mauricio; Räisänen, Ismo T.; Contreras, Johanna; Tervahartiala, Taina; Chaparro, Alejandra; Sorsa, Timo; Hernández-Ríos, Patricia 
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PB  -  
Y1  - 2021 
LA  - eng 
AB  - Periodontitis is a host-mediated bacterial disease that affects the tooth attachment apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical diagnosis. This study aimed to evaluate the diagnostic performance of active (a) MMP-8 immunotest versus total (t) MMP-8 ELISA for quantitative real-time diagnosis and assessment of periodontitis severity at the site level. Gingival crevicular fluid (GCF) was sampled from 30 healthy, 42 mild, and 59 severe periodontitis sites fr... 
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KW  - Biomarkers; Diagnosis; Gingival crevicular fluid; Matrix metalloproteinase-8; Periodontal disease; Periodontitis; NEUTROPHIL COLLAGENASE ACTIVITY; matrix metalloproteinase-8; biomarkers; MARKERS; diagnosis; GINGIVAL CREVICULAR FLUID; CLASSIFICATION; MATRIX METALLOPROTEINASE-8; periodontal disease; BIOMARKERS; TISSUE DESTRUCTION; periodontitis; gingival crevicular fluid; DEGRADATION; HEALTH; PROGRESSION; 313 Dentistry 
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