TY - T1 - Advances in lipidomics SN - / UR - http://hdl.handle.net/10138/332472 T3 - A1 - Avela, Henri F.; Siren, Heli A2 - PB - Y1 - 2020 LA - eng AB - The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with multivariate data analysis. This review specifically targets lipid biomarkers and disease pathway mechanisms in humans and artificial targets. Different ... VO - IS - SP - OP - KW - Lipids; Liquid chromatography; Tandem mass spectrometry; Clinical profiles; Biomarkers; Blood; PERFORMANCE LIQUID-CHROMATOGRAPHY; TANDEM MASS-SPECTROMETRY; FIELD-FLOW FRACTIONATION; PLATELET-ACTIVATING-FACTOR; ESI-QTOF-MS/MS; ELECTROSPRAY-IONIZATION; LC-MS/MS; SAMPLE PREPARATION; STRUCTURAL-CHARACTERIZATION; POTENTIAL BIOMARKERS; 116 Chemical sciences N1 - PP - ER -