TY  -  
T1  - Aging and serum exomiR content in women-effects of estrogenic hormone replacement therapy 
SN  -  /  
UR  - http://hdl.handle.net/10138/177046 
T3  -  
A1  - Kangas, Reeta; Tormakangas, Timo; Fey, Vidal; Pursiheimo, Juha; Miinalainen, Ilkka; Alen, Markku; Kaprio, Jaakko; Sipila, Sarianna; Saamanen, Anna-Marja; Kovanen, Vuokko; Laakkonen, Eija K. 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Exosomes participate in intercellular messaging by transporting bioactive lipid-, protein-and RNA-molecules and -complexes. The contents of the exosomes reflect the physiological status of an individual making exosomes promising targets for biomarker analyses. In the present study we extracted exosome microRNAs (exomiRs) from serum samples of premenopausal women (n = 8) and monozygotic postmenopausal twins (n = 10 female pairs), discordant for the use of estrogenic hormone replacement therapy (H... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - MONOZYGOTIC TWIN PAIRS; POSTMENOPAUSAL WOMEN; BODY-COMPOSITION; SKELETAL-MUSCLE; BREAST-CANCER; MICRORNAS; EXPRESSION; DISCORDANT; CELLS; MENOPAUSE; 3111 Biomedicine 
N1  -   
PP  -  
ER  -