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T1  - Alcohol and substance use are associated with altered metabolome in the first trimester serum samples of pregnant mothers 
SN  -  /  
UR  - http://hdl.handle.net/10138/299132 
T3  -  
A1  - Lehikoinen, Anni I.; Kärkkäinen, Olli K.; Lehtonen, Marko A.S.; Auriola, Seppo O.K.; Hanhineva, Kati J.; Heinonen, Seppo T. 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Background: Although the effects of alcohol on metabolic processes in the body have been studied widely, there do not appear to be any previous reports clarifying how substance abuse changes metabolic profiles of pregnant women during the first trimester of pregnancy. Objective: Our aim was to evaluate the effect of substance abuse, especially alcohol use, on the metabolic profile of pregnant women during the first trimester. Study design: We applied mass spectrometry based non-targeted metaboli... 
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KW  - 3123 Gynaecology and paediatrics; Alcohol; Metabolomics; Metabolism; Pregnancy; Prenatal diagnosis; Smoking; BIOCHEMICAL MARKERS; ADDICTION; DEPENDENCE; RESONANCE-SPECTROSCOPY; CENTRAL GLUTAMATE; ETHANOL; USE DISORDERS; CONSUMPTION; BRAIN 
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