TY - T1 - Amphetamine primes enhanced motivation toward uncertain choices in rats with genetic alcohol preference SN - / UR - http://hdl.handle.net/10138/311373 T3 - A1 - Oinio, Ville; Sundström, Mikko; Bäckström, Pia; Uhari-Väänänen, Johanna; Kiianmaa, Kalervo; Raasmaja, Atso; Piepponen, Petteri A2 - PB - Y1 - 2018 LA - eng AB - Comorbidity with gambling disorder (GD) and alcohol use disorder (AUD) is well documented. The purpose of our study was to examine the influence of genetic alcohol drinking tendency on reward-guided decision making behavior of rats and the impact of dopamine releaser D-amphetamine on this behavior. In this study, Alko alcohol (AA) and Wistar rats went through long periods of operant lever pressing training where the task was to choose the profitable of two options. The lever choices were guided ... VO - IS - SP - OP - KW - Gambling; Alcohol use disorder; Decision making; D-Amphetamine; Rats; POPULATION-BASED SAMPLE; PREFERRING AA RATS; AVOIDING ANA RATS; DECISION-MAKING; VOLUNTARY ALCOHOL; DOPAMINE NEURONS; PATHOLOGICAL GAMBLERS; HEALTHY CONTROLS; FAMILY-HISTORY; USE DISORDER; 3112 Neurosciences; 317 Pharmacy N1 - PP - ER -