TY  -  
T1  - Amyloid tracers binding sites in autosomal dominant and sporadic Alzheimer's disease 
SN  -  /  
UR  - http://hdl.handle.net/10138/236747 
T3  -  
A1  - Ni, Ruiqing; Gillberg, Per-Goran; Bogdanovic, Nenad; Viitanen, Matti; Myllykangas, Liisa; Nennesmo, Inger; Langstrom, Bengt; Nordberg, Agneta 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Introduction: Amyloid imaging has been integrated into diagnostic criteria for Alzheimer's disease (AD). How amyloid tracers binding differ for different tracer structures and amyloid-beta aggregates in autosomal dominant AD (ADAD) and sporadic AD is unclear. Methods: Binding properties of different amyloid tracers were examined in brain homogenates from six ADAD with APPswe, PS1 M146V, and PS1 E Delta 9 mutations, 13 sporadic AD, and 14 control cases. Results: H-3-PIB, H-3-florbetaben, H-3-AZD2... 
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KW  - Alzheimer's disease; Amyloid-beta; Autosomal dominant Alzheimer's disease; Positron emission tomography; Resveratrol; Pittsburgh compound B; AZD2184; Florbetaben; POSITRON-EMISSION-TOMOGRAPHY; MILD COGNITIVE IMPAIRMENT; PITTSBURGH COMPOUND B; A-BETA; SPASTIC PARAPARESIS; MUTATION CARRIERS; MOLECULAR-DYNAMICS; BRAIN-TISSUE; IN-VIVO; PET; 3112 Neurosciences; 3124 Neurology and psychiatry 
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