TY - T1 - An interaction between NDE1 and high birth weight increases schizophrenia susceptibility SN - / UR - http://hdl.handle.net/10138/203727 T3 - A1 - Wegelius, Asko; Pankakoski, Maiju; Tomppo, Liisa; Lehto, Ulriika; Lonnqvist, Jouko; Suvisaari, Jaana; Paunio, Tiina; Hennah, William A2 - PB - Y1 - 2015 LA - eng AB - Pre- and perinatal environmental factors have been shown to increase schizophrenia risk particularly when combined with genetic liability. The investigation of specific gene environment interactions in the etiology of psychiatric disorders has gained momentum. We used multivariate GEE regression modeling to investigate the interaction between genes of the DISCI pathway and birth weight, in relation to schizophrenia susceptibility in a Finnish schizophrenia family cohort. The study sample consist... VO - IS - SP - OP - KW - Birth weight; Neurodevelopment; Schizophrenia; Gene; Environment; DISC1; NDE1; FETAL-GROWTH; OBSTETRIC COMPLICATIONS; ENVIRONMENT INTERACTION; GENE-ENVIRONMENT; RISK-FACTORS; FAMILIES; HYPOXIA; FINLAND; COHORT; 3124 Neurology and psychiatry N1 - PP - ER -