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T1  - An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper (R) 
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UR  - http://hdl.handle.net/10138/190726 
T3  -  
A1  - Varga, Zsuzsanna; Lebeau, Annette; Bu, Hong; Hartmann, Arndt; Penault-Llorca, Frederique; Guerini-Rocco, Elena; Schraml, Peter; Symmans, Fraser; Stoehr, Robert; Teng, Xiaodong; Turzynski, Andreas; von Wasielewski, Reinhard; Guertler, Claudia; Laible, Mark; Schlombs, Kornelia; Joensuu, Heikki; Keller, Thomas; Sinn, Peter; Sahin, Ugur; Bartlett, John; Viale, Giuseppe 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Background: Accurate determination of the predictive markers human epidermal growth factor receptor 2 (HER2/ERBB2), estrogen receptor (ER/ESR1), progesterone receptor (PgR/PGR), and marker of proliferation Ki67 (MKI67) is indispensable for therapeutic decision making in early breast cancer. In this multicenter prospective study, we addressed the issue of inter- and intrasite reproducibility using the recently developed reverse transcription-quantitative real-time polymerase chain reaction-based ... 
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KW  - MammaTyper; Reproducibility; RT-qPCR; FFPE; Breast cancer; ERBB2; ESR1; PGR; MKI67; RECURRENCE SCORE; AMERICAN-SOCIETY; RECEPTOR EXPRESSION; DISTANT RECURRENCE; ESTROGEN-RECEPTOR; ENDOCRINE THERAPY; WORKING GROUP; RT-QPCR; KI67; RECOMMENDATIONS; 3122 Cancers 
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