TY  -  
T1  - Analysis of macroautophagy and mitophagy in patient fibroblasts with a rare infantile lysosomal storage disorder 
SN  -  /  
UR  - URN:NBN:fi:hulib-202012094864; http://hdl.handle.net/10138/322560 
T3  -  
A1  - Butkovic, Rebeka 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2020 
LA  - eng 
AB  - Autophagy is a cellular recycling and quality control process that eliminates cellular material in a non-selective or selective fashion. Macroautophagy is non-selective, and degrades macromolecules or damaged organelles to sustain cellular homeostasis. The selective autophagy of dysfunctional or excess mitochondria is known as mitophagy. The clinical importance of functional degradation is exemplified by the lysosomal storage disorders (LSDs), where lysosomal hydrolytic enzymes are absent or dys... 
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KW  - autophagy; mitophagy; lysosomal storage disorders; mitochondria; Solu- ja kehitysbiologia; Cell and Developmental Biology; Cell- och utvecklingsbiologi; Genetiikan ja molekulaaristen biotieteiden maisteriohjelma; Master's Programme in Genetics and Molecular Biosciences; Magisterprogrammet i genetik och molekylära biovetenskaper 
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ER  -