TY  -  
T1  - Anti-EDAR Agonist Antibody Therapy Resolves Palate Defects in Pax9 -/- Mice 
SN  -  /  
UR  - http://hdl.handle.net/10138/299388 
T3  -  
A1  - Jia, S.; Zhou, J.; Wee, Y.; Mikkola, M. L.; Schneider, P.; D'Souza, R. N. 
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Y1  - 2017 
LA  - eng 
AB  - To date, surgical interventions are the only means by which craniofacial anomalies can be corrected so that function, esthetics, and the sense of well-being are restored in affected individuals. Unfortunately, for patients with cleft palate-one of the most common of congenital birth defects-treatment following surgery is prolonged over a lifetime and often involves multidisciplinary regimens. Hence, there is a need to understand the molecular pathways that control palatogenesis and to translate ... 
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KW  - developmental biology; cleft palate; craniofacial biology/genetics; morphogenesis; gene expression; therapeutic treatment; LINKED ECTODERMAL DYSPLASIA; HAIR FOLLICLE INDUCTION; RECEPTOR EDAR; CLEFT-LIP; KAPPA-B; ECTODYSPLASIN; MORPHOGENESIS; BMP4; MSX1; PAX9; 313 Dentistry 
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