TY  -  
T1  - Antileishmanial activity of extracts from Libidibia ferrea : development of in vitro and in vivo tests 
SN  -  /  
UR  - http://hdl.handle.net/10138/231174 
T3  -  
A1  - Comandolli-Wyrepkowski, Claudia Dantas; Jensen, Bruno Bezerra; Grafova, Iryna; dos Santos, Pierre Alexandre; Comapa Barros, Angela Maria; Soares, Fabiane Veloso; Marques Barcellos, Jose Fernando; da Silva, Aline Fagundes; Grafov, Andriy; Ramos Franco, Antonia Maria 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Treatment of cutaneous leishmaniasis (CL) is difficult due to the scarce number of drugs able to eliminate completely the intracellular form of the parasite. In the present study, the aim was to evaluate: i) phytochemical properties of extracts from Libidibia ferrea; ii) antileishmanial activity of extracts from L. ferrea against promastigotes and amastigotes of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) guyanensis; iii) the effects of topical treatment using hydrogel containin... 
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KW  - cutaneous leishmaniasis; natural products; topical formulations; experimental treatment; EXPERIMENTAL CUTANEOUS LEISHMANIASIS; CAESALPINIA-FERREA; TOPICAL TREATMENT; DRUG DEVELOPMENT; BALB/C MICE; ANTIOXIDANT; FRUITS; FORMULATION; TARGETS; MART; 116 Chemical sciences; 317 Pharmacy; 3141 Health care science 
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ER  -