TY - T1 - Antimalarial Activity of Croton macrostachyus Stem Bark Extracts against Plasmodium berghei In Vivo SN - / UR - http://hdl.handle.net/10138/238346 T3 - A1 - Obey, Jackie K.; Ngeiywa, Moses M.; Kiprono, Paul; Omar, Sabah; von Wright, Atte; Kauhanen, Jussi; Tikkanen-Kaukanen, Carina A2 - PB - Y1 - 2018 LA - eng AB - There is an increasing need for innovative drug and prophylaxis discovery against malaria. The aim of the present study was to test in vivo antiplasmodial activity of Croton macrostachyus H. (Euphorbiaceae) stem bark extracts from Kenyan folkloric medicine. Inbred Balb/c mice were inoculated with erythrocytes parasitized with Plasmodium berghei (ANKA). Different doses (500, 250, and 100mg/kg) of C. macrostachyus ethyl acetate, methanol, aqueous, and isobutanol extracts were administrated either ... VO - IS - SP - OP - KW - BIOACTIVE COMPOUNDS; FALCIPARUM-MALARIA; AMPHIPHILES; MEFLOQUINE; 1183 Plant biology, microbiology, virology N1 - PP - ER -