TY  -  
T1  - Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model 
SN  -  /  
UR  - http://hdl.handle.net/10138/240224 
T3  -  
A1  - Kuryk, Lukasz; Moller, Anne-Sophie W.; Garofalo, Mariangela; Cerullo, Vincenzo; Pesonen, Sari; Alemany, Ramon; Jaderberg, Magnus 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Oncolytic adenoviral immunotherapy activates the innate immune system with subsequent induction of adaptive tumor-specific immune responses to fight cancer. Hence, oncolytic viruses do not only eradicate cancer cells by direct lysis, but also generate antitumor immune response, allowing for long-lasting cancer control and tumor reduction. Their therapeutic effect can be further enhanced by arming the oncolytic adenovirus with costimulatory transgenes and/or coadministration with other antitumor ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - granulocyte-macrophage colony-stimulating factor (GM-CSF); mesothelin; mesothelioma; oncolytic adenovirus; ONCOS-102; NEUTRALIZING ANTIBODIES; IMMUNOTHERAPY; CHEMOTHERAPY; IMMUNITY; VACCINE; VIRUSES; 1183 Plant biology, microbiology, virology; 317 Pharmacy 
N1  -   
PP  -  
ER  -