TY  -  
T1  - Antitumoral Effect of Plocabulin in High Grade Serous Ovarian Carcinoma Cell Line Models 
SN  -  /  
UR  - http://hdl.handle.net/10138/343203 
T3  -  
A1  - Heredia-Soto, Victoria; Escudero, Javier; Miguel, María; Ruiz, Patricia; Gallego, Alejandro; Berjón, Alberto; Hernández, Alicia; Martínez-Díez, Marta; Zheng, Shuyu; Tang, Jing; Hardisson, David; Feliu, Jaime; Redondo, Andrés; Mendiola, Marta 
A2  -  
PB  -  
Y1  - 2022 
LA  - eng 
AB  - Ovarian cancer (OC) is a life-threatening tumor and the deadliest among gynecological cancers in developed countries. First line treatment with a carboplatin/paclitaxel regime is initially effective in the majority of patients, but most advanced OC will recur and develop drug resistance. Therefore, the identification of alternative therapies is needed. In this study, we employed a panel of high-grade serous ovarian cancer (HGSOC) cell lines, in monolayer and three-dimensional cell cultures. We e... 
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IS  -  
SP  -  
OP  -  
KW  - 3D cell culture; CANCER; DOUBLE-BLIND; MAINTENANCE THERAPY; SYNERGY; drug testing; high-grade serous ovarian cancer (HGSOC); microtubule inhibitor; plocabulin (PM060184); 3122 Cancers 
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ER  -