TY  -  
T1  - Apparent nosocomial adaptation of Enterococcus faecalis predates the modern hospital era 
SN  -  /  
UR  - http://hdl.handle.net/10138/329311 
T3  -  
A1  - Pöntinen, Anna K.; Top, Janetta; Arredondo-Alonso, Sergio; Tonkin-Hill, Gerry; Freitas, Ana R.; Novais, Carla; Gladstone, Rebecca A.; Pesonen, Maiju; Meneses, Rodrigo; Pesonen, Henri; Lees, John A.; Jamrozy, Dorota; Bentley, Stephen D.; Lanza, Val F.; Torres, Carmen; Peixe, Luisa; Coque, Teresa M.; Parkhill, Julian; Schurch, Anita C.; Willems, Rob J. L.; Corander, Jukka 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Enterococcus faecalis is a commensal and nosocomial pathogen, which is also ubiquitous in animals and insects, representing a classical generalist microorganism. Here, we study E. faecalis isolates ranging from the pre-antibiotic era in 1936 up to 2018, covering a large set of host species including wild birds, mammals, healthy humans, and hospitalised patients. We sequence the bacterial genomes using short- and long-read techniques, and identify multiple extant hospital-associated lineages, wit... 
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KW  - 1184 Genetics, developmental biology, physiology; 112 Statistics and probability 
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