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T1  - Arabidopsis downy mildew effector HaRxL106 suppresses plant immunity by binding to RADICAL-INDUCED CELL DEATH1 
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UR  - http://hdl.handle.net/10138/244929 
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A1  - Wirthmueller, Lennart; Asai, Shuta; Rallapalli, Ghanasyam; Sklenar, Jan; Fabro, Georgina; Kim, Dae Sung; Lintermann, Ruth; Jaspers, Pinja; Wrzaczek, Michael; Kangasjärvi, Jaakko; MacLean, Daniel; Menke, Frank L. H.; Banfield, Mark J.; Jones, Jonathan D. G. 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - The oomycete pathogen Hyaloperonospora arabidopsidis (Hpa) causes downy mildew disease on Arabidopsis. To colonize its host, Hpa translocates effector proteins that suppress plant immunity into infected host cells. Here, we investigate the relevance of the interaction between one of these effectors, HaRxL106, and Arabidopsis RADICAL-INDUCED CELL DEATH1 (RCD1). We use pathogen infection assays as well as molecular and biochemical analyses to test the hypothesis that HaRxL106 manipulates RCD1 to a... 
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KW  - Arabidopsis thaliana; Hyaloperonospora arabidopsidis; oomycete pathogen; pathogen effector; plant innate immunity; RADICAL-INDUCED CELL DEATH1; salicylic acid (SA); SYSTEMIC ACQUIRED-RESISTANCE; PHYTOPHTHORA-INFESTANS; SALICYLIC-ACID; HISTONE H3; TRANSCRIPTIONAL REPRESSOR; JASMONATE RESPONSES; PATHOGEN EFFECTORS; AUXIN BIOSYNTHESIS; DISORDERED PROTEIN; INNATE IMMUNITY; 1183 Plant biology, microbiology, virology 
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