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T1  - Around the clock : gradient shape and noise impact the evolution of oscillatory segmentation dynamics 
SN  -  /  
UR  - http://hdl.handle.net/10138/299515 
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A1  - Vroomans, Renske M. A.; Hogeweg, Paulien; ten Tusscher, Kirsten H. W. J. 
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PB  -  
Y1  - 2018 
LA  - eng 
AB  - BackgroundSegmentation, the subdivision of the major body axis into repeated elements, is considered one of the major evolutionary innovations in bilaterian animals. In all three segmented animal clades, the predominant segmentation mechanism is sequential segmentation, where segments are generated one by one in anterior-posterior order from a posterior undifferentiated zone. In vertebrates and arthropods, sequential segmentation is thought to arise from a clock-and-wavefront-type mechanism, whe... 
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KW  - Segmentation; Travelling waves; Oscillations; Complexity; Robustness; MODEL; SOMITOGENESIS; TRANSITIONS; UNDERLIES; NETWORK; NOTCH; WNT; 318 Medical biotechnology 
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