TY - T1 - Assay optimization and validation for screening marine extracts against Mycobacterium smegmatis SN - / UR - URN:NBN:fi-fe201801151227; http://hdl.handle.net/10138/40067 T3 - A1 - Kuosmanen, Soile A2 - PB - Helsingfors universitet Y1 - 2013 LA - eng AB - The lower respiratory infection tuberculosis (TB) has been the leading cause of death for centuries causing millions of deaths worldwide. The development of antibiotic therapy has reduced the morbidity and mortality during the 20th century, at least in the developed countries. However, tuberculosis is still the world's second leading cause of death from infectious diseases. Although TB can be treated and even cured with drug therapy, the treatment is extremely long and requires 6-9 months consta... VO - IS - SP - OP - KW - MDR; XDR; MIC; Tuberculosis; Resistance; Mycobacterium smegmatis; Antimicrobial activity; Turbidimetric; Colorimetric; Quality parameter; resistenssi; antimikrobinen aktiivisuus; turbidimetrinen; kolorimetrinen; laatuparametri; tuberkuloosi; Farmakognosi; Pharmacognosy; Farmakognosia N1 - PP - ER -