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T1  - Assessment of blinding may be inappropriate after the trial : [Letter] 
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UR  - http://hdl.handle.net/10138/228099 
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A1  - Hemilä, Harri 
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PB  -  
Y1  - 2005 
LA  - eng 
AB  - In their paper discussing the assessment of blinding in clinical trials, Bang et al. based their analysis on the premise that "all participants randomly guess their assignment... This is the most ideal scenario in reality". However, this premise makes an implicit assumption that the drug does not differ from placebo in any physiological effects that a person could observe subjectively, which is a very strong assumption. If a drug is truly effective, such as penicillin for pneumococcal pneumonia,... 
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KW  - VITAMIN-C; COMMON COLD; ASCORBIC-ACID; DISSENT; 314 Health sciences 
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ER  -