TY  -  
T1  - Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality : data from the FINNAKI observational study 
SN  -  /  
UR  - http://hdl.handle.net/10138/305658 
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A1  - FINNAKI Study Grp 
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PB  -  
Y1  - 2019 
LA  - eng 
AB  - Background Injury to endothelium and glycocalyx predisposes to vascular leak, which may subsequently lead to increased fluid requirements and worse outcomes. In this post hoc study of the prospective multicenter observational Finnish Acute Kidney Injury (FINNAKI) cohort study conducted in 17 Finnish intensive care units, we studied the association of Syndecan-1 (SDC-1), Angiopoetin-2 (Ang-2), soluble thrombomodulin (sTM), vascular adhesion protein-1 (VAP-1) and interleukin-6 (IL-6) with fluid ad... 
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KW  - Biomarker; Glycocalyx; Sepsis; Fluid balance; Fluid resuscitation; Soluble thrombomodulin; Acute kidney injury; VASCULAR ADHESION PROTEIN-1; SURVIVING SEPSIS CAMPAIGN; SEPTIC SHOCK; SOLUBLE THROMBOMODULIN; ORGAN FAILURE; GUIDELINES; SYNDECAN-1; DISEASE; VOLUME; RISK; 3126 Surgery, anesthesiology, intensive care, radiology; 3121 General medicine, internal medicine and other clinical medicine 
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