TY  -  
T1  - Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment 
SN  -  /  
UR  - http://hdl.handle.net/10138/335350 
T3  -  
A1  - NBCS Collaborators; ABCTB Investigators; kConFab Investigators; Morra, Anna; Escala-Garcia, Maria; Beesley, Jonathan; Muranen, Taru A.; Nevanlinna, Heli 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Background Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast cancer patients. Methods We performed genome-wide association analyses within 15 subgroups of breast cancer patients based on prognostic factors, including hormone receptors, tumor grade, age, and type of systemic treatment. Analyses were based on 91,686 female patients of Euro... 
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KW  - Common germline genetic variants; Breast cancer-specific survival; Patient subgroups; Tumor biology; Systemic treatment; BETA-CATENIN; EXPRESSION; SUSCEPTIBILITY; PROGNOSIS; SUBTYPES; IDENTIFICATION; PROGRESSION; ROLES; LOCI; TOOL; 3122 Cancers 
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