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T1  - Association of plasma gelsolin with frailty phenotype and mortality among octogenarian community-dwelling men : a cohort study 
SN  -  /  
UR  - http://hdl.handle.net/10138/345171 
T3  -  
A1  - Strandberg, Timo E.; Levinson, Susan L.; DiNubile, Mark J.; Jyväkorpi, Satu; Kivimäki, Mika 
A2  -  
PB  -  
Y1  - 2022 
LA  - eng 
AB  - Background Biomarkers are needed for frailty, a common phenotype often associated with muscle loss in older people. Plasma gelsolin (pGSN) is a protein largely synthesized and secreted by skeletal muscle. Aims To investigate whether pGSN could be a biomarker of the frailty phenotype and predict mortality. Methods A homogenous cohort of males (born 1919-1934, baseline n = 3490) has been followed since the 1960s. In 2010/11, frailty phenotypes by modified Fried criteria were assessed. pGSN was mea... 
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KW  - Biomarker; Prefrailty; Sarcopenia; MARKER; MUSCLE; 3111 Biomedicine; 3121 General medicine, internal medicine and other clinical medicine 
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ER  -