TY  -  
T1  - Astrocytes in Neuropathologies Affecting the Frontal Cortex 
SN  -  /  
UR  - http://hdl.handle.net/10138/300212 
T3  -  
A1  - Peteri, Ulla-Kaisa; Niukkanen, Mikael; Castren, Maija L. 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - To an increasing extent, astrocytes are connected with various neuropathologies. Astrocytes comprise of a heterogeneous population of cells with region- and species-specific properties. The frontal cortex exhibits high levels of plasticity that is required for high cognitive functions and memory making this region especially susceptible to damage. Aberrations in the frontal cortex are involved with several cognitive disorders, including Alzheimer's disease, Huntington's disease and frontotempora... 
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KW  - astrocyte; frontal cortex; Alzheimer's disease; Huntington's disease; frontotemporal dementia; neurodegeneration; induced pluripotent stem cells; FIBRILLARY ACIDIC PROTEIN; PREFRONTAL CORTEX; MUTANT HUNTINGTIN; MOUSE MODEL; FRONTOTEMPORAL DEMENTIA; GLUTAMATE RELEASE; INCREASED EXPRESSION; STRIATAL ASTROCYTES; D-SERINE; DISEASE; 3112 Neurosciences; 3124 Neurology and psychiatry 
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