TY - T1 - Autograft cellular composition and outcome in myeloma patients: Results of the prospective multicenter GOA study SN - / UR - http://hdl.handle.net/10138/336123 T3 - A1 - Turunen, A; Silvennoinen, R; Partanen, A; Valtola, J; Siitonen, T; Putkonen, M; Sankelo, M; Pyorala, M; Kuittinen, T; Penttila, K; Sikio, A; Savolainen, ER; Mantymaa, P; Pelkonen, J; Varmavuo, V; Jantunen, E A2 - PB - Y1 - 2021 LA - eng AB - Background Autologous stem cell transplantation (auto-SCT) is a widely used treatment option in multiple myeloma (MM) patients. The optimal graft cellular composition is not known. Study design and methods Autograft cellular composition was analyzed after freezing by flow cytometry in 127 MM patients participating in a prospective multicenter study. The impact of graft cellular composition on hematologic recovery and outcome after auto-SCT was evaluated. Results A higher graft CD34(+) cell conte... VO - IS - SP - OP - KW - 3122 Cancers; autograft cellular composition; autologous stem cell transplantation; CD34(+) cells; hematologic recovery; myeloma; NK cells; outcome; T lymphocytes; HIGH-DOSE CHEMOTHERAPY; SINGLE-CENTER EXPERIENCE; NON-HODGKIN-LYMPHOMA; MULTIPLE-MYELOMA; PERIPHERAL-BLOOD; HEMATOPOIETIC STEM; AUTOLOGOUS TRANSPLANTATION; FREE SURVIVAL; PREDICTIVE FACTORS; CD34(+) CELLS N1 - PP - ER -