TY  -  
T1  - Autophagy Genes for Wet Age-Related Macular Degeneration in a Finnish Case-Control Study 
SN  -  /  
UR  - http://hdl.handle.net/10138/326796 
T3  -  
A1  - Paterno, Jussi J.; Koskela, Ali; Hyttinen, Juha M. T.; Vattulainen, Elina; Synowiec, Ewelina; Tuuminen, Raimo; Watala, Cezary; Blasiak, Janusz; Kaarniranta, Kai 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Age-related macular degeneration is an eye disease that is the main cause of legal blindness in the elderly in developed countries. Despite this, its pathogenesis is not completely known, and many genetic, epigenetic, environmental and lifestyle factors may be involved. Vision loss in age-related macular degeneration (AMD) is usually consequence of the occurrence of its wet (neovascular) form that is targeted in the clinic by anti-VEGF (vascular endothelial growth factor) treatment. The wet form... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - aging; autophagy; degeneration; macula; neovascularization; RETINAL-PIGMENT EPITHELIUM; RANIBIZUMAB TREATMENT; ASSOCIATION; ARMS2; DELETION; RPE; CFH; 3125 Otorhinolaryngology, ophthalmology 
N1  -   
PP  -  
ER  -