TY - T1 - BCNNM : A Framework for in silico Neural Tissue Development Modeling SN - / UR - http://hdl.handle.net/10138/328176 T3 - A1 - Bozhko, Dmitrii V.; Galumov, Georgii K.; Polovian, Aleksandr I.; Kolchanova, Sofiia M.; Myrov, Vladislav O.; Stelmakh, Viktoriia A.; Schioth, Helgi B. A2 - PB - Y1 - 2021 LA - eng AB - Cerebral ("brain") organoids are high-fidelity in vitro cellular models of the developing brain, which makes them one of the go-to methods to study isolated processes of tissue organization and its electrophysiological properties, allowing to collect invaluable data for in silico modeling neurodevelopmental processes. Complex computer models of biological systems supplement in vivo and in vitro experimentation and allow researchers to look at things that no laboratory study has access to, due to... VO - IS - SP - OP - KW - brain organoid; tissue development; neurogenesis; simulation; axon guidance; neuronal connectivity; 3112 Neurosciences; 3124 Neurology and psychiatry N1 - PP - ER -