TY - T1 - BRAF immunohistochemistry predicts sentinel lymph node involvement in intermediate thickness melanomas SN - / UR - http://hdl.handle.net/10138/303863 T3 - A1 - Manninen, Atte A.; Gardberg, Maria; Juteau, Susanna; Ilmonen, Suvi; Jukonen, Joonas; Andersson, Noora; Carpen, Olli A2 - PB - Y1 - 2019 LA - eng AB - Background Sentinel node biopsy (SNB) is an important step in melanoma staging and prognostication. It is commonly performed for patients with intermediate thickness melanomas, based on clinicopathological features. However, only 20-25% of patients eventually demonstrate nodal involvement. The aim of this study was to evaluate whether tissue biomarkers with links to melanoma biology, together with clinicopathological parameters, could aid in the prediction of sentinel node involvement and improv... VO - IS - SP - OP - KW - MUTATIONS; BIOPSY; EZRIN; PATHWAYS; V600E; 3111 Biomedicine N1 - PP - ER -